SPECIFIC FEATURES OF ANTIBIOTICS RESISTANCE IN CHILDREN WITH ENT PATHOLOGY

Abstract

Antibiotic resistance is a phenomenon in which bacteria become insensitive to antibiotics that are intended to eliminate them. The main causes of this process are excessive or improper prescription and use of antibiotics, including selfmedication, as well as their widespread use in animal husbandry. Treating infections caused by resistant microorganisms is much more difficult or even impossible. Thus, antibiotic resistance leads to increased mortality from infectious diseases and becomes a real threat for modern medicine. Bacterial resistance poses a particular danger for children, since the range of drugs used in pediatrics is much smaller due to their specific effects on the childrens’ body. In the course of this study, we analyzed data from patients who were hospitalized in the head and neck surgery department of Kyiv City Children’s Clinical Hospital №2 in 2024 and received antibacterial therapy. The aim was to investigate the dynamics of antibiotic resistance depending on such factors as gender, age, diagnosis, and type of persistent pathogen. Using mathematical methods and computer programming, we were able to determine individual resistance indicators for various microorganisms, as well as assess the effectiveness of different antibacterial drugs. The results obtained may be useful in the practice of pediatric otolaryngologists for prescribing and adjusting treatment, and also emphasize the importance of optimizing and controlling antibiotic prescriptions for doctors of all specialties.